yes, I believe you can -- especially in aspects with the ruling planet of your chart (the planet associated with your Ascendant) or any planets closely parked on one of the 4 angles -- in my case both Pluto and Mercury
also planets at either 0 degrees or 29 degrees of any sign are also "hot spots" with "extra potential" for growth -- and growth often comes as a result of some type of "pain"
Saturn is another place that shows where "the lessons are"; question: are lessons karmic debt
or spiritual reward ??